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Skeletal Muscles
...  in the presence of stimulus. The contraction starts when calcium ions begin to leak from the endoplasmic reticulum. Due to the changes in the electrical potential inside and outside of the cell, the muscle fibers begin to shorten. Collectively, they pull the bones to create motion. Muscle Fatigue Muscle fatigue is a normal phenomenon when your muscles experience too much stress. It happens to  ...

Cholinergic Stimulation
...  vesicles release the chemical in the synapse, causing the calcium channels to open. The binding of the chemical with the acetylcholine receptor leads to the influx of sodium in the cytoplasm of the muscle fiber. When the original stimulus ceases, cholinergic stimulation stops through the degradation of the chemical. The enzyme acetylcholine esterase splits the substance into two; namely, the  ...


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