Lyrica

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Lyrica

Lyrica, known in its generic name as Pregabalin, is a medication taken orally to treat seizures, postherpetic neuralgia and other problems caused by neurological ailments. This medication is also used to treat the complications brought about by fibromyalgia.

How Lyrica Works

The medication works by binding the calcium and nerve channels in the body. Such bond will adjust the neurotransmitter discharge occurring within the body, as well as those chemicals being used by the nerves for their communication with others.

Things To Consider Before Taking Lyrica

Lyrica has several interactions when taken with alcohol and other drugs. When Lyrica is mixed with alcohol, it is said to have sedative effects. Lyrica treatment mixed with Pioglitazone or rosigitazone can induce weight gain or fluid retention (or a combination) among patients. Such mixture also causes heart failure. Thus, it is important to consult doctor about taking Lyrica along with other medications.

It is not yet proven if Lyrica has effect among unborn babies, or if it passes through breast milk. However, it is best to consult the doctor about Lyrica intake if you are pregnant (or planning to be pregnant) or nursing.

Dosage And Administration

Lyrica is available in a variety of doses: 25mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg to 300mg in capsule form. Its efficiency and potency is maintained when the medication is stored at temperatures between 15 to 30 degrees Celsius.

Dosage and administration of this drug depends on the patient’s condition, including the medical, drug and allergy history. Normally, those with neuralgia start off with 50mg-75mg a day taken two to three times. Doctors recommend a total of 150 milligrams a day divided in several doses- preferably, 3 doses a day. If the doctor has approved, the dose could be increased to 100 mg divided to 3 doses, or a total of 300 mg a day after a week or two of intake. Patients normally cannot take a dose higher than 300 mg a day, as it could lead to side effects which cannot be tolerated by the health. However, for those with seizure and similar problems may take 150 mg to 600 mg a day, divided into several doses. Those with Fibromyalgia can take 300 mg to 450 mg a day divided in several doses.

Lyrica is safe for intake, even without meals.

Side Effects

Common side effects include edema or bloating, dizziness, cloudy vision, dry mouth, sudden weight gain, and loss of coordination. Other side effects which could be severe include reduce of blood platelet or increase of creatinine kinase, thus increasing risk of heart attack.

Patients should seek medical help if any of these occur.

Other Details

Lyrica has the molecular formula C8H17NO2 and the IUPAC name 3-(aminomethyl)-5-methyl-hexanoic acid. It weighs at 159.226 g/mol. 

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